Allele frequencies data and statistic parameters for 15 STR loci in a southern Moroccan population

Noura Dahbi, Khadija Cheffi, Abderrazak El khair, Lamiaa Habbibeddine, Jalal Talbi, Abderraouf Hilali, Hicham El ossmani

Abstract


Shor t tandem repeats (STRs) are particularly informative markers with a high level of variability. They are widely used in anthropological studies to quantitatively characte rize the relationships between individuals in the same or distinct populations. In this study, 15 autosomal STR markers (D5S818, FGA, D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, VWA, TPOX, and D18S51) were PCR amplified using AmpFlSTR® IdentifilerTM Kit (Applied Biosystems, Foster City, CA, USA) [1] in order to study the genetic diversity of a population in the sou th of Morocco. A sample of over 100 healthy unrelated individuals was studied. Allele frequencies, Hardy Weinberg equilibrium and forensic parameters were calculated us i ng Arlequin v3.5.2.2 [2] and STRAF ( 1.0.5: STR Analysis for Forensics) [3]. The findings show a significant deviation from equilibrium for three markers even after Bonferroni correction: TH01, VWA, and D18S5 1 . All loci are highly polymorphic, with D18S51 showing the highest polymorphism. The combined power of discrimination and exclusion was significantly high, suggesting that this panel is relevant for forensic casework.


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DAHBI ET AL 2022

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