Fluorometric Sensing of Hexavalent Chromium in waste water and living cells by C dot decorated biocompatible FeOOH nanoparticles

Bidisha Ghosh

Abstract


Chromium is accounted as one of the most recognized carcinogenic heavy metal. It is found in nature as trivalent chromium Cr (III) and hexavalent (VI)[1]. Cr (VI) has many deleterious effects in the body and has been seen to cause defects in RBC formation [2]. The present work focuses on using in-situ synthesized carbon quantum dots into the goethite (α-FeOOH) nano-matrix and then fluorometric detection of hazardous hexavalent chromium Cr (VI)) in wastewater and Cr (VI) contaminated live cells is being performed the nano-hybrid has a potential for identifying the of chromium contamination levels in various types of water samples. This fluorometric probe is extremely sensitive to hexavalent chromium having a LOD 81nM making it a specialized chromium sensor. Furthermore, the sensing process has been evaluated using Stern-equation Volmer's and fluorescence lifetime studies, which revealed that photoinduced electron transfer and the inner filter effect occur simultaneously. This chromium sensor has also been used to determine the level of pollution in actual industrial effluent. The sensing performance of the probe when tested in a real-world wastewater sample is pretty impressive. This biocompatible fluorometric sensor has also been utilized to demonstrate Cr (VI) sensing in HeLa cells in vitro. Theoretical docking simulations have been used to validate the rapid detection mechanism of hexavalent chromium in real cells. This fluorometric sensor material can be assumed to open up new possibilities in wastewater monitoring and biomedical applications in the future.

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GHOSH ET AL

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